Center Introduction
The National Industrial Innovation Center for Bio-manufacturing was approved for establishment by the National Development and Reform Commission on July 11, 2023, and is the only national-level industrial innovation platform in China's bio-manufacturing sector.
The center is led by the Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, in collaboration with 34 upstream and downstream leading enterprises in the industry chain, including the United Nations Investment Group and China Merchants Group. It focuses on the major national strategic industrial needs, concentrating on the 1-10 pilot scale-up stages of biomanufacturing, exploring the transformation of the traditional linear model from laboratory to enterprise into a nonlinear interactive model, and promoting the high-quality development of China's biomanufacturing industry.
Central Location: Guangming Science City Yinxing Synthetic Biology Industrial Park
Land area: approximately 47,000 square meters
The center focuses on pilot-scale amplification in the field of biomanufacturing from 1 to 10, serving the stages that laboratories cannot handle and companies are unwilling to do, and is involved in key areas such as green low-carbon, bio-agriculture, and healthcare, changing the original linear transformation model from laboratory to enterprise into a nonlinear interactive model.
Application Process
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| Submit enterprise or project information for application | The expert review committee conducts project evaluations | Officially move into the center after passing the review | Receive comprehensive policy and service support |
Relevant institutions
The National Bio-manufacturing Industry Innovation Center forms close ecological linkages with important research institutions and universities in the surrounding area.
Guangming Science City
The core carrier of the comprehensive national science center in the Guangdong-Hong Kong-Macao Greater Bay Area, enjoying national-level policy and funding support, focusing on future industries such as biological manufacturing.
Major Infrastructure for Synthetic Biology Research
The world's largest high-throughput, automated synthetic biology platform, equipped with a 10,000-liter fermentation tank cluster and automated DBTL platform, significantly reducing corporate R&D costs.
Shenzhen Institute of Synthetic Biology Innovation
Led by the Shenzhen Advanced Institute, focusing on the design and synthesis of artificial life systems, integrating BT and IT technologies, committed to breaking through key synthetic biology technologies and promoting their application demonstrations.
Shenzhen Institute of Advanced Technology
Directly operated by the Shenzhen Advanced Institute of the Chinese Academy of Sciences, the first batch established the School of Synthetic Biology (the only one in the country), innovatively implementing "college system + project system" training, and is the source of talent and technology reserves for the National Innovation Center.
Sun Yat-sen University Shenzhen Campus
Planned to cover about 5,000 mu (the largest university land in Shenzhen), focusing on medical-engineering integration and new interdisciplinary subjects, with multiple medical-related schools such as the School of Biomedical Engineering and the School of Pharmacy.
One-Stop Service System
Equipment & Space
Providing standardized and customized service models, covering space leasing and equipment leasing, helping enterprises reduce upfront investment and quickly start R&D and production.
(1) Standardized space and equipment leasing: on-demand matching of incubation space + open shared instrument equipment.
(2) Customized space and equipment procurement: on-demand planning of customized space + personalized production line setup.
Enabling Technology
Providing professional technical services for small-scale and pilot-scale process development, verification and optimization in bio-manufacturing, including fermentation process optimization services, pilot purification services, AI informatics services, engineering general contracting services, production commissioning services and third-party testing services.
Specialized Consulting &Incubation
Providing enterprise project declaration guidance services, intellectual property/medical device registration certificate pre-review services, technology transformation matching services, startup operation support services and technology finance services.
Marketing Service
The National Innovation Center launches a core product promotion platform, with online mini-program one-click access and offline exhibition hall real experience. Connecting the full-link closed loop from technology display to order landing, driving efficient transaction completion.
Core platforms
Breaking through frontier technology bottlenecks and promoting industrial agglomeration
Automated Biomanufacturing Platform
Based on an information architecture and high-throughput equipment, leveraging a fully automated cell product construction system integrated with AI parameter optimization, enabling chassis cell design and construction, phenotypic screening, sample preparation, and standardized target testing, accelerating full-process innovation.
Large-Scale Vector Preparation and Quality Control Platform
Focused on large-scale vector production, leveraging specialized equipment to break through common technical bottlenecks, integrated with AI production control, achieving scale-up production and quality control of vector preparations, supporting the engineering preparation of viral and biomimetic vectors.
High-Throughput Process Development Platform
Integrating Industry 4.0 and sensor technology, leveraging a 1.5L-50L fermentation system, based on AI fermentation scale-up algorithms, achieving fine control of process parameters from lab to pilot scale, improving fermentation process development efficiency and success rate.
Pilot Scale-Up and GMP Platform
Focusing on biological macromolecular products, viral drugs, bacterial drugs, and cell drugs, leveraging 50mL-30L bioreactors and fermentation systems, integrated with AI process optimization models, providing full-chain services from pilot scale-up and clinical declaration to standardized production, offering stable and reliable data support for large-scale manufacturing.
Cross-Scale Biological Multimodal Validation Platform
Integrating AI and high-resolution imaging technology, leveraging advanced detection methods and animal experiments, establishing standardized animal model evaluation systems, empowering disease model construction and precision target screening.
Bioinformatics Computing Support Platform
Based on bioinformatics and AI technology, leveraging high-performance computing clusters and big data analysis systems, conducting intelligent analysis and decision support for the entire biomanufacturing process data, providing data analysis and visualization support for all platforms.
